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Leukopenia
exists whenever the number of the white blood cells in the peripheral
circulation is continually lower than 4¡Á109/L, and the percentage of
neutrophilic granulocytes is normal or slightly decreased. In most cases, the
disease is related to the decrease of neutrophilic granulocytes, and
granulocytopenia is defined as the absolute number of granulocytes is reduced
below 1.8¡ª2¡Á109/L. In TCM, this disease is grouped into the
categories of "xuan yun" (vertigo), "xu lao" (consumptive
diseases), etc.
Main Points of
Diagnosis
1.
There must be a history of facilitating the result of leukopenia, e.g. contact
with X-ray or radioactive materials, administration of drugs that affect
leucocytes ,such as Amidopy-rine, Butazolidin, Thiouracil, Sulfonamides and
antitumor agents, etc. Virus infection, desmosis and hepersplenism may also
cause leukopenia.
2.
The patient may be sick with such symptoms as dizziness, fatigue, mild fever,
amprexoa and insomnia. The disease is chronic and is frequently accompanied with
infections.
3.
Leukocyte count ranges 2¡ª4¡Á109/L, with normal or slightly reduced
percentage of granulocytes. The picture of bone marrow shows no specific change.
4.
The provocative test of adrenalin is helpful for identifying the false
leukopenia. Hydrocortisone test can be used to test the reserving energy of bone
marrow, indicating treatment and prognosis.
Differentiation
and Treatment of Common Syndromes
1.
Deficiency of Both Qi and Yin
Main
Symptoms and Signs: Dim complexion, dizziness, blurred vision, lassitude and
weakness, dysphoria with feverish sensation in the chest, palms and soles, pink
tongue with little fur, thready and weak or thready and rapid pulse.
Therapeutic
Principle: Supplementing qi and nourishing yin.
Recipe:
Pulse-Activating Powder with additional ingredients.
pseudostellaria
root
ophiopogon
root
schisandra
berry
astragalus
root,
siberian
solomonseal rhizome
spatholobus
stem
tortoise
plastron
prepared
licorice
All
the above herbs are to be decocted in water for oral administration.
In
addition to the above ingredients, drugs of prepared rehmannia root 15g, dogwood
fruit 12g and wolfberry fruit 15g are needed for cases with severe deficiency of
the liver-yin and kidney-yin marked by amnesia, tinnitus, soreness and weakness
in the loins and knees, tidal fever, night sweat, etc.
2.
Insufficiency of Both the Spleen and Stomach
Main
Symptoms and Signs: Vertigo, emaciation, lassitude, anorexia, indigestion,
abdominal distension and fullness, sallow complexion, loose stool, pale tongue
with whitish fur, thready and weak pulse.
Therapeutic
Principle: Strengthening the spleen and replenishing qi.
Recipe:
Modified Prescriptions of Decoction of Four Noble Herbs and Astragalus Decoction
for Tonifying the Middle-Warmer.
codonopsis root
white
atractylodes rhizome
poria
prepared
licorice
astragalus
root
cinnamon
twig
white
peony root
Chinese
date
hyacinth
bean
Chinese
yam
amommum
fruit
chicken's
gizzard
All
the above herbs are to be decocted in water for oral administration.
3.
Deficiency of the Spleen-Yang and Kidney-Yang
Main
Symptoms and Signs: Dizziness, tinnitus ,fatigue and weakness, deficiency of qi
,disinclination to talk, intolerance of cold, cold limbs, aching pain and
weakness in the loins and knees, poor appetite, loose stool, or puffy face and
edema of limbs, pale and tender tongue with thin and whitish or whitish and
greasy fur, deep, thready and weak pulse.
Therapeutic
Principle: Warming and replenishing the spleen and kidney.
Recipe:
Modified Prescriptions of Aconite Decoction for Regulating the Function of
Middle-Warmer and Kidney-Yang Reinforcing Bolus.
prepared
aconite root
dried
ginger
codonopsis
root
white
atractylodes rhizome
poria
eucommia
bark
antler
glue (melted in boiling water)
dodder
seed
astragalus
root
prepared
licorice
All
the above herbs are to be decocted in water for oral administration.
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